PREVENTION OF RhD ALLOIMMUNIZATION IN RhD NEGATIVE WOMEN
نویسندگان
چکیده
منابع مشابه
[Guideline for prevention of RhD alloimmunization in RhD negative women].
Events following which anti-D immunoglobulin should be given to all RhD negative women with no anti-D antibodies: First trimester indications (50 microg)--termination of pregnancy, spontaneous abortion followed by instrumentation, ectopic pregnancy, chorionic villus sampling, partial molar pregnancy; Second and third trimester indications (100 microg)--amniocentesis, cordocentesis, other invasi...
متن کاملMolecular RHD screening of RhD negative donors can replace standard serological testing for RhD negative donors.
This work aims to assess the value of a generalized molecular RHD screening strategy which could replace routine serological screening of weak D by indirect antiglobulin test. Three independent studies were performed at the two Blood Transfusion Services Berne and Zurich. Donors investigated were 652 RhD negative, but RhC and/or RhE positive, 17,391 mainly Rhccee, and 8200 with normal RhCcEe ph...
متن کاملEffect of high throughput RHD typing of fetal DNA in maternal plasma on use of anti-RhD immunoglobulin in RhD negative pregnant women: prospective feasibility study.
OBJECTIVES To assess the feasibility of applying a high throughput method, with an automated robotic technique, for predicting fetal RhD phenotype from fetal DNA in the plasma of RhD negative pregnant women to avoid unnecessary treatment with anti-RhD immunoglobulin. DESIGN Prospective comparison of fetal RHD genotype determined from fetal DNA in maternal plasma with the serologically determi...
متن کاملFetal RHD Genotyping Using Real-Time Polymerase Chain Reaction Analysis of Cell-Free Fetal DNA in Pregnancy of RhD Negative Women in South of Iran
Objective Maternal-fetal RhD antigen incompatibility causes approximately 50% of clinically significant alloimmunization cases. The routine use of prophylactic anti-D immunoglobulin has dramatically reduced hemolytic disease of the fetus and newborn. Recently, fetal RHD genotyping in RhD negative pregnant women has been suggested for appropriate use of anti-D immunoglobulin antenatal prophylaxi...
متن کاملNoninvasive fetal RHD genotyping using cell-free fetal DNA incorporating fetal RASSF1A marker in RhD-negative pregnant women in Korea
risk of HDFN, which can cause fetal anemia, hydrops, and intrauterine fetal death. Babies born with HDFN are at significant risk of neonatal morbidity and mortality [1,2]. Prenatal detection of the fetal RhD status in a pregnant woman with RhD-negative provides useful information for predicting the risk of HDFN and Noninvasive fetal RHD genotyping using cell-free fetal DNA incorporating fetal R...
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ژورنال
عنوان ژورنال: Biomedical Papers
سال: 2010
ISSN: 1213-8118,1804-7521
DOI: 10.5507/bp.2010.003